While a nagging ache in your shoulder might seem harmless, doctors warn it could be a subtle sign of cancer.
Experts say a persistent ‘phantom’ pain in the right shoulder can, in some cases, signal liver cancer, even when the arm itself feels completely normal.
Once considered a disease of older people, liver cancer is now increasingly being diagnosed in adults in their 30s and 40s – raising alarm among experts.
It is also on course to become a far bigger global health crisis, with cases expected to double by 2050.
The disease is already one of the fastest-rising in the UK, yet its symptoms are often vague and easy to dismiss.
Around 6,000 people are diagnosed each year, with rates soaring by more than 40 per cent over the past decade.
Dr Jiri Kubes, medical director at the Proton Therapy Centre in Prague, said that one warning sign in particular is frequently misunderstood – and ignored.
‘Liver cancer can sometimes cause what we call referred or phantom pain, where discomfort is felt in the shoulder rather than the abdomen,’ he explained.
While a nagging ache in your shoulder might seem harmless, doctors warn it could be a subtle sign of a deadly – yet often preventable – cancer
‘This happens because the liver sits close to nerves that connect to the shoulder, so irritation can be felt elsewhere in the body.’
The pain is typically felt on the right-hand side and may come and go – making it easy to brush off as a minor strain.
Dr Kubes added that many patients assume it is caused by exercise or poor posture, particularly if they are otherwise fit and active.
Yet liver cancer is now one of the fastest-rising causes of cancer death in the UK, with lifestyle factors playing a major role.
The biggest risks include long-term alcohol use, obesity, fatty liver disease, hepatitis B and C infections and smoking, with many cases linked to liver damage that develops silently over years.
‘The challenge with liver cancer is that symptoms can be very subtle at first,’ Dr Kubes said. ‘People often ignore them or put them down to something harmless.’
However, experts stress that many cases are preventable.
Maintaining a healthy weight, limiting alcohol intake and protecting against hepatitis infections can all significantly reduce risk.
Other warning signs include feeling full quickly after eating, unexplained weight loss, swelling or bloating in the abdomen, and yellowing of the skin or eyes.
Because liver cancer is often diagnosed at a late stage, recognising these early symptoms could prove life-saving.
A major analysis published in The Lancet last year linked the rise in younger cases to obesity and related liver conditions, including fatty liver disease – now one of the fastest-growing causes of liver cancer worldwide.
Experts say a more severe form of the condition, known as MASH, is becoming increasingly common and is strongly linked to weight gain and poor metabolic health.
Cases driven by obesity and alcohol are expected to rise sharply in the coming decades, even as those caused by hepatitis infections decline.
