{"id":8856,"date":"2026-05-03T22:52:14","date_gmt":"2026-05-03T22:52:14","guid":{"rendered":"https:\/\/www.healthoptibody.com\/?p=8856"},"modified":"2026-05-05T15:57:58","modified_gmt":"2026-05-05T15:57:58","slug":"i-have-my-own-funeral-planned-down-to-the-smallest-detail-meet-irelands-death-doulas-who-specialise-in-making-the-dyings-final-days-as-easy-as-possible-and-help-ease-the-pain-for-those-they-l","status":"publish","type":"post","link":"https:\/\/www.healthoptibody.com\/?p=8856","title":{"rendered":"Pembrolizumab injection vs IV | NHS National Cancer Plan 2026 | Keytruda side effects"},"content":{"rendered":"<p>&nbsp;<\/p>\n<div>\n<h3 data-path-to-node=\"6\">\ud83d\udcdd The 60-Second Breakthrough: NHS Immunotherapy Goes &#8220;Rapid&#8221;<\/h3>\n<p data-path-to-node=\"7\">The NHS is officially rolling out a revolutionary injectable form of immunotherapy that treats over a dozen different cancers in as little as <b data-path-to-node=\"7\" data-index-in-node=\"142\">60 seconds<\/b>. This move is expected to transform the lives of roughly <b data-path-to-node=\"7\" data-index-in-node=\"210\">14,000 patients<\/b> in England every year, slashing treatment times by a staggering <b data-path-to-node=\"7\" data-index-in-node=\"290\">90%<\/b>.<\/p>\n<p data-path-to-node=\"8\">The drug, <b data-path-to-node=\"8\" data-index-in-node=\"10\">pembrolizumab<\/b> (brand name <b data-path-to-node=\"8\" data-index-in-node=\"36\">Keytruda<\/b>), was previously administered via an intravenous (IV) infusion that could take up to two hours per session. The new &#8220;jab&#8221; is a subcutaneous injection delivered into the fatty tissue of the abdomen or thigh.<\/p>\n<h4 data-path-to-node=\"9\"><b data-path-to-node=\"9\" data-index-in-node=\"0\">Which Cancers are Eligible?<\/b><\/h4>\n<p data-path-to-node=\"10\">The rapid jab is approved for <b data-path-to-node=\"10\" data-index-in-node=\"30\">14 different types of cancer<\/b>, including:<\/p>\n<ul data-path-to-node=\"11\">\n<li>\n<p data-path-to-node=\"11,0,0\">Lung Cancer<\/p>\n<\/li>\n<li>\n<p data-path-to-node=\"11,1,0\">Breast Cancer<\/p>\n<\/li>\n<li>\n<p data-path-to-node=\"11,2,0\">Head and Neck Cancers<\/p>\n<\/li>\n<li>\n<p data-path-to-node=\"11,3,0\">Cervical Cancer<\/p>\n<\/li>\n<\/ul>\n<div class=\"mol-img-group floatLHS\">\n<div class=\"mol-img\">\n<div class=\"image-wrap\"><img fetchpriority=\"high\" decoding=\"async\" id=\"i-9c47b245857a39b8\" class=\"blkBorder img-share\" style=\"max-width: 100%;\" src=\"https:\/\/i.dailymail.com\/1s\/2026\/05\/03\/22\/108345811-15787197-Sarah_Gardiner-a-5_1777845188850.jpg\" alt=\"Sarah Gardiner\" width=\"306\" height=\"449\" \/><\/div>\n<\/div>\n<p class=\"imageCaption\">Sarah Gardiner<\/p>\n<\/div>\n<h3 data-path-to-node=\"13\">\ud83e\uddec How It Works: &#8220;Unmasking&#8221; the Disease<\/h3>\n<p data-path-to-node=\"14\">Pembrolizumab is a form of <b data-path-to-node=\"14\" data-index-in-node=\"27\">immunotherapy<\/b>. Unlike traditional chemotherapy, which attacks all fast-growing cells, this drug &#8220;teaches&#8221; the body to fight back.<\/p>\n<ul data-path-to-node=\"15\">\n<li>\n<p data-path-to-node=\"15,0,0\"><b data-path-to-node=\"15,0,0\" data-index-in-node=\"0\">The Target:<\/b> It blocks a protein called <b data-path-to-node=\"15,0,0\" data-index-in-node=\"39\">PD-1<\/b>.<\/p>\n<\/li>\n<li>\n<p data-path-to-node=\"15,1,0\"><b data-path-to-node=\"15,1,0\" data-index-in-node=\"0\">The Mechanism:<\/b> PD-1 usually acts as a &#8220;brake&#8221; on the immune system. Cancer cells often hijack this protein to hide from immune responses.<\/p>\n<\/li>\n<li>\n<p data-path-to-node=\"15,2,0\"><b data-path-to-node=\"15,2,0\" data-index-in-node=\"0\">The Result:<\/b> By blocking the &#8220;brake,&#8221; the drug allows the immune system to recognize and aggressively attack the cancer cells.<\/p>\n<\/li>\n<\/ul>\n<hr data-path-to-node=\"16\" \/>\n<h3 data-path-to-node=\"17\">\u23f1\ufe0f The Impact on NHS Capacity<\/h3>\n<p data-path-to-node=\"18\">With a diagnosis made in the UK every <b data-path-to-node=\"18\" data-index-in-node=\"38\">75 seconds<\/b>, the NHS is currently facing a capacity crisis. Last year, over <b data-path-to-node=\"18\" data-index-in-node=\"113\">106,000 patients<\/b> waited more than 62 days for urgent treatment.<\/p>\n<table data-path-to-node=\"19\">\n<thead>\n<tr>\n<td><strong>Feature<\/strong><\/td>\n<td><strong>Old Method (IV Infusion)<\/strong><\/td>\n<td><strong>New Method (Injection)<\/strong><\/td>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><span data-path-to-node=\"19,1,0,0\"><b data-path-to-node=\"19,1,0,0\" data-index-in-node=\"0\">Treatment Time<\/b><\/span><\/td>\n<td><span data-path-to-node=\"19,1,1,0\">Up to 120 Minutes<\/span><\/td>\n<td><span data-path-to-node=\"19,1,2,0\">1 to 2 Minutes<\/span><\/td>\n<\/tr>\n<tr>\n<td><span data-path-to-node=\"19,2,0,0\"><b data-path-to-node=\"19,2,0,0\" data-index-in-node=\"0\">Frequency<\/b><\/span><\/td>\n<td><span data-path-to-node=\"19,2,1,0\">Every 3 to 6 weeks<\/span><\/td>\n<td><span data-path-to-node=\"19,2,2,0\">Every 3 to 6 weeks<\/span><\/td>\n<\/tr>\n<tr>\n<td><span data-path-to-node=\"19,3,0,0\"><b data-path-to-node=\"19,3,0,0\" data-index-in-node=\"0\">Location<\/b><\/span><\/td>\n<td><span data-path-to-node=\"19,3,1,0\">Infusion Unit Chair<\/span><\/td>\n<td><span data-path-to-node=\"19,3,2,0\">General Treatment Room<\/span><\/td>\n<\/tr>\n<tr>\n<td><span data-path-to-node=\"19,4,0,0\"><b data-path-to-node=\"19,4,0,0\" data-index-in-node=\"0\">System Benefit<\/b><\/span><\/td>\n<td><span data-path-to-node=\"19,4,1,0\">High resource\/staff time<\/span><\/td>\n<td><span data-path-to-node=\"19,4,2,0\">Frees up clinical appointments<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p data-path-to-node=\"20\"><b data-path-to-node=\"20\" data-index-in-node=\"0\">Health Secretary Wes Streeting<\/b> noted that this rollout is a core part of the <b data-path-to-node=\"20\" data-index-in-node=\"77\">National Cancer Plan<\/b>, which aims to meet all existing cancer targets by <b data-path-to-node=\"20\" data-index-in-node=\"149\">March 2028<\/b> through innovation and the use of a &#8220;robotic revolution&#8221; to boost survival rates.<\/p>\n<div class=\"mol-img-group floatRHS\">\n<div class=\"mol-img\">\n<div class=\"image-wrap\"><img decoding=\"async\" id=\"i-66a976e1fcdd903b\" class=\"blkBorder img-share\" style=\"max-width: 100%;\" src=\"https:\/\/i.dailymail.com\/1s\/2026\/05\/03\/22\/108345813-15787197-image-m-5_1777844141318.jpg\" alt=\"Bernadette Kenny\" width=\"306\" height=\"345\" \/><\/div>\n<\/div>\n<p class=\"imageCaption\">Bernadette Kenny<\/p>\n<\/div>\n<h3 data-path-to-node=\"22\">\u26a0\ufe0f Side Effects &amp; Considerations<\/h3>\n<p data-path-to-node=\"23\">While the rapid administration is a triumph of convenience, the underlying medicine remains a powerful metabolic therapy. Side effects occur regardless of whether the drug is injected or given via IV.<\/p>\n<p data-path-to-node=\"24\"><b data-path-to-node=\"24\" data-index-in-node=\"0\">Common Side Effects:<\/b><\/p>\n<ul data-path-to-node=\"25\">\n<li>\n<p data-path-to-node=\"25,0,0\"><b data-path-to-node=\"25,0,0\" data-index-in-node=\"0\">Hypothyroidism:<\/b> A drop in thyroid hormones can lead to fatigue, weight gain, and depression. Patients may require lifelong hormone replacement therapy.<\/p>\n<\/li>\n<li>\n<p data-path-to-node=\"25,1,0\"><b data-path-to-node=\"25,1,0\" data-index-in-node=\"0\">Breathlessness:<\/b> Often caused by a drop in red blood cell counts.<\/p>\n<\/li>\n<li>\n<p data-path-to-node=\"25,2,0\"><b data-path-to-node=\"25,2,0\" data-index-in-node=\"0\">Fluid Build-up:<\/b> General swelling or edema.<\/p>\n<\/li>\n<\/ul>\n<p data-path-to-node=\"26\"><b data-path-to-node=\"26\" data-index-in-node=\"0\">Rare but Serious Risks:<\/b> In rare cases, the immune system can become overactive and attack healthy organs, leading to:<\/p>\n<ul data-path-to-node=\"27\">\n<li>\n<p data-path-to-node=\"27,0,0\"><b data-path-to-node=\"27,0,0\" data-index-in-node=\"0\">Encephalitis<\/b> (brain inflammation)<\/p>\n<\/li>\n<li>\n<p data-path-to-node=\"27,1,0\"><b data-path-to-node=\"27,1,0\" data-index-in-node=\"0\">Pancreatitis<\/b><\/p>\n<\/li>\n<li>\n<p data-path-to-node=\"27,2,0\"><b data-path-to-node=\"27,2,0\" data-index-in-node=\"0\">Myocarditis<\/b> (heart inflammation)<\/p>\n<\/li>\n<\/ul>\n<p class=\"mol-para-with-font\">broke us.<\/p>\n<div class=\"mol-img-group floatLHS\">\n<div class=\"mol-img\">\n<div class=\"image-wrap\"><img decoding=\"async\" id=\"i-a5c57e8cc0e4eb63\" class=\"blkBorder img-share\" style=\"max-width: 100%;\" src=\"https:\/\/i.dailymail.com\/1s\/2026\/05\/03\/22\/108345809-15787197-image-m-8_1777844193441.jpg\" alt=\"Jessica Byrne\" width=\"306\" height=\"439\" \/><\/div>\n<\/div>\n<p class=\"imageCaption\">Jessica Byrne<\/p>\n<\/div>\n<h3 data-path-to-node=\"29\">\ud83d\udca1 The Takeaway<\/h3>\n<p data-path-to-node=\"30\">For patients like 89-year-old <b data-path-to-node=\"30\" data-index-in-node=\"30\">Shirley Xerxes<\/b>, the first to receive the jab, the benefit is measured in hours reclaimed. &#8220;I was only in the chair for a matter of minutes instead of an hour or more,&#8221; she shared. &#8220;It gives me more time to live my life, including spending more time gardening.&#8221;<\/p>\n<p data-path-to-node=\"31\">By making &#8220;every penny and every second count,&#8221; the NHS is betting that this 60-second solution will be a vital tool in bringing down the UK&#8217;s daunting cancer backlog.<\/p>\n<hr data-path-to-node=\"32\" \/>\n<p data-path-to-node=\"33\"><b data-path-to-node=\"33\" data-index-in-node=\"0\">Are you or a loved one currently navigating a cancer treatment plan? This shift to injections could significantly change your hospital schedule\u2014is this a move you&#8217;ve been waiting for?<\/b><\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>&nbsp; \ud83d\udcdd The 60-Second Breakthrough: NHS Immunotherapy Goes &#8220;Rapid&#8221; The NHS is officially rolling out a revolutionary injectable form of immunotherapy that treats over a dozen different cancers in as little as 60 seconds. This move is expected to transform the lives of roughly 14,000 patients in England every year, slashing treatment times by a<\/p>\n","protected":false},"author":1,"featured_media":8857,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[987],"tags":[3552,3948,2585,3947,1359,1363,3472,3949,2586,3421],"class_list":{"0":"post-8856","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-healthy-living","8":"tag-cancer-treatment","9":"tag-healthcare-efficiency","10":"tag-immunotherapy","11":"tag-keytruda","12":"tag-medical-innovation","13":"tag-nhs","14":"tag-oncology","15":"tag-patient-care","16":"tag-pembrolizumab","17":"tag-uk-health"},"_links":{"self":[{"href":"https:\/\/www.healthoptibody.com\/index.php?rest_route=\/wp\/v2\/posts\/8856","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.healthoptibody.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.healthoptibody.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.healthoptibody.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.healthoptibody.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=8856"}],"version-history":[{"count":2,"href":"https:\/\/www.healthoptibody.com\/index.php?rest_route=\/wp\/v2\/posts\/8856\/revisions"}],"predecessor-version":[{"id":8970,"href":"https:\/\/www.healthoptibody.com\/index.php?rest_route=\/wp\/v2\/posts\/8856\/revisions\/8970"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.healthoptibody.com\/index.php?rest_route=\/wp\/v2\/media\/8857"}],"wp:attachment":[{"href":"https:\/\/www.healthoptibody.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=8856"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.healthoptibody.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=8856"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.healthoptibody.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=8856"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}