{"id":7850,"date":"2026-04-14T12:43:48","date_gmt":"2026-04-14T12:43:48","guid":{"rendered":"https:\/\/www.healthoptibody.com\/?p=7850"},"modified":"2026-04-14T12:43:48","modified_gmt":"2026-04-14T12:43:48","slug":"women-with-osteoporosis-more-likely-to-carry-alzheimers-risk-gene-concerning-new-study-suggests","status":"publish","type":"post","link":"https:\/\/www.healthoptibody.com\/?p=7850","title":{"rendered":"Women with osteoporosis ‘more likely to carry Alzheimer’s risk gene’, concerning new study suggests"},"content":{"rendered":"

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By MARTI STELLING, HEALTH REPORTER<\/a> <\/p>\n

Published:<\/span>

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Women diagnosed with osteoporosis may have a higher chance of carrying a gene linked to Alzheimer’s<\/a> disease, according to new research. <\/p>\n

Scientists found that APOE4 – the most common genetic risk factor for Alzheimer’s – can weaken bone quality in women, even when standard scans appear normal.<\/p>\n

The study, carried out by researchers at the Buck Institute for Research on Ageing in California<\/a>, US and UC San Francisco, suggests the gene may damage bone at a microscopic level long before any visible signs.<\/p>\n

These changes can emerge as early as midlife and remain invisible to routine imaging tests used to assess bone strength.<\/p>\n

The findings, published in the journal Advanced Science, suggest a link between Alzheimer’s risk and skeletal health – and could help pave the way for earlier detection of both conditions.<\/p>\n

Doctors have long observed that people with Alzheimer’s suffer higher rates of bone fractures, while osteoporosis in women is known to be one of the earliest predictors of the disease.<\/p>\n

Now scientists believe they may have uncovered why.<\/p>\n

Researchers led by Dr Charles Schurman carried out a detailed analysis of proteins in aged mouse bone and found that tissue was unusually rich in molecules linked to neurological disease, including those associated with Alzheimer’s.<\/p>\n

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Women with osteoporosis may be more likely to carry a gene linked to Alzheimer’s disease, according to new research<\/p>\n<\/div>\n